Psychiatric Mental Health, part 38: Disorders - Alzheimer's Disease & Dementia vs. Delirium

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In this video/article, we cover Alzheimer's disease and the differences between dementia and delirium.

This series follows along with our Psychiatric Mental Health Nursing Flashcards which are intended to help RN and PN nursing students study for nursing school exams, including the ATI, HESI, and NCLEX.

Alzheimer's disease

Alzheimer's disease is gradual, irreversible dementia that results in memory problems, judgment issues, and changes in personality. Neurons are specialized cells in the nervous system (which includes the brain) that process and transmit information, including thought, memory, and language. Though the exact mechanisms are unknown, Alzheimer's damages neurons and other brain areas.

Risk factors for Alzheimer's

Risk factors for Alzheimer's disease include older age, a family history of Alzheimers, and cardiovascular disease.

Alzheimer's disease signs and symptoms

Symptoms of Alzheimer's disease will vary depending on whether the patient is in early-, moderate-, or late-stage Alzheimer's. There are also some general signs of Alzheimer's disease that may occur regardless of its stage.

Early-stage Alzheimer's

Symptoms of early-stage Alzheimer's include forgetfulness, short-term memory loss, and mild cognitive impairment.

Moderate-stage Alzheimer's

Symptoms of moderate-stage Alzheimer's disease include disorientation, agitation, as well as incontinence and wandering. People with moderate-stage Alzheimer's disease typically require help with their ADLs (activities of daily living).

Late-stage Alzheimer's

During late-stage Alzheimer's disease, patients will become bedridden, lose their verbal and motor skills, and experience dysphagia (difficulty swallowing)

Other signs and symptoms of Alzheimer's

Other signs and symptoms of Alzheimer's disease that may occur in any stage include confabulation, preservation, and sundowning.

Confabulation

Confabulation is the creation of false memories. It is important to understand a patient who exhibits confabulation is not purposefully lying or intending to deceive anyone. It is a compensatory mechanism that happens with Alzheimer's to fill in gaps in memory.

Preservation

Preservation is another symptom of dementia. This is where the patient repeats words, phrases, or gestures over and over again.

Sundowning

Sundowning is an increase in agitation or aggression in the evening that often presents with Alzheimer's. In this video, Cathy points out that if you end up working the night shift on a med-surg floor or in a SNF or LTAC, you are pretty likely to see sundowning in action. A patient may be very calm and agreeable during the day, but in the evening, agitation and aggression can spike.

Diagnosis of Alzheimer's

Diagnosis of Alzheimer's disease includes a review of the patient's symptoms, memory and thinking tests, as well as ruling out underlying causes of the patient's symptoms. A definitive diagnosis of Alzheimer's would only come after a brain examination after the patient's death.

Alzheimer's treatment

Treatment options for Alzheimer's disease include medications like memantine and donepezil, which can help improve a patient's cognition. It is theorized that Alzheimer's is associated with the loss of cholinergic neurons, and donepezil is a cholinergic, so it works to stop the loss of the cholinergic neurons. It's important to note that these medications do not cure Alzheimer's disease.

Other medications such as antipsychotics, antidepressants, and anxiolytics can be used to help manage the patient's symptoms.

All of these medications are covered in our Pharmacology - Nursing Flashcards.

Nursing care

Nursing care of a patient with Alzheimer's disease is heavily tested on in nursing school. As a nurse, maintain a structured environment. Provide the patient with short directions, repetition, and frequent reorientation. Overstimulation of patients with Alzheimer's should be avoided. Use of a single-day calendar is recommended. It's also important to maintain a routine toileting schedule.

In terms of home safety, it's important to advise the family or caretaker to remove clutter from the home as well as remove scatter rugs, which can be a tripping hazard. Cathy points out that nursing school exams are obsessed with scatter rugs — so remember, no scatter rugs!

Door locks should be installed out of sight and out of patient reach due to wandering behavior. There should be good lighting in the home, particularly over the stairs, and step edges can be marked with colored tape to make it clear where those step edges are—this can help prevent falls.

Differences between dementia and delirium

To understand the difference between dementia and delirium, let's first define them.

Dementia

Dementia is chronic, irreversible confusion that is caused by a neurodegenerative disease, e.g., Alzheimer's disease.

Delirium

Delirium is temporary and reversible confusion that is caused by an underlying disorder such as an electrolyte imbalance or infection.

Onset

Dementia has a gradual onset. Delirium has an acute or sudden onset.

Prognosis

Dementia is chronic, progressive, and irreversible. Delirium is transient (temporary) and reversible.

Cause

Dementia is usually caused by a neurodegenerative disease, e.g., Alzheimer's disease. Delirium can be caused by metabolic disorders, infections, or toxins.

Level of consciousness

Level of consciousness is a patient's level of alertness or arousability. A normal finding is for the patient to be alert.

With dementia, a person's level of consciousness is usually unchanged. With delirium, alterations in levels of consciousness are typically present.

Behavior

In patients with dementia, behavior is typically normal until advanced stages of the disease. In patients with delirium, behavior can be very disturbed. Patients experiencing delirium can be easily distracted and may experience hallucinations and sleep/wake disturbances.

Quiz Questions

What is the term for creation of false memories to fill in memory gaps?

Confabulation

To prevent falls in the home, scatter rugs should be removed. True or false?

True

Donepezil is a medication used to cure Alzheimer's disease. True or false?

False. Donepezil can help improve cognition in a patient with Alzheimer's disease, but it will not cure the disease.

An altered level of consciousness is expected with dementia. True or false?

False. An altered level of consciousness often occurs with delirium, but not with dementia.

Delirium has a sudden onset and is reversible. True or false?

True

Full Transcript: Psychiatric Mental Health, part 38: Disorders - Alzheimer's Disease & Dementia vs. Delirium

Hi, I'm Cathy with Level Up RN. In this video, we will be talking about Alzheimer's disease as well as the differences between dementia and delirium. And at the end of the video, I'm going to give you guys a little quiz to test your knowledge of some of the key points I'll be covering in the video, so definitely stay tuned for that. And as always, I will be following along with our Level Up RN psychiatric mental health nursing flashcards. If you have our flashcards, be sure to pay close attention to the bold red text on these cards because those represent the most important facts that you are likely to get tested on in nursing school.

Alzheimer's disease is gradual, irreversible dementia that results in memory problems, judgment issues, and changes in personality. Symptoms of Alzheimer's disease will vary depending on whether the patient is in early-, moderate-, or late-stage Alzheimer's. Symptoms of early-stage Alzheimer's include forgetfulness, short-term memory loss, and mild cognitive impairment. Symptoms of moderate-stage Alzheimer's disease include disorientation, agitation, as well as incontinence and wandering. Individuals in moderate-stage Alzheimer's disease typically require help with their ADLs or activities of daily living. Then during late-stage Alzheimer's disease, patients will become bedridden, and they will lose their verbal and motor skills. And dysphagia, or difficulty swallowing, also occurs during the stage. Another symptom that can occur with Alzheimer's disease is something called confabulation, which is the creation of false memories. So to be clear, a patient who exhibits confabulation is not lying or intending to deceive anyone. They are simply trying to fill in gaps in their memory. Preservation is another symptom of dementia. This is where the patient repeats words, phrases, or gestures over and over again. And then sundowning is very common with Alzheimer's disease. This is an increase in agitation or aggression in the evening. So if you end up working the night shift on a med-surg floor or in a SNF or LTAC, you will definitely see this in action. A patient may be very calm and agreeable during the day, but in the evening, they can get really out of hand.

Diagnosis of Alzheimer's disease includes a review of the patient's symptoms, memory and thinking tests, as well as ruling out underlying causes of the patient's symptoms. Treatment options include medications such as memantine and donepezil, which can help improve cognition in patients with Alzheimer's disease. However, it's important to note that these medications do not cure Alzheimer's disease. Other medications such as antipsychotics, antidepressants, and anxiolytics can also be used to help manage the patient's symptoms.

Nursing care of the patient with Alzheimer's disease is heavily tested on in nursing school. As the nurse, you need to maintain a structured environment. You need to provide the patient with short directions, repetition, and frequent reorientation. Overstimulation of the patient should be avoided. Use of a single-day calendar is recommended. And then it's also important to maintain a routine toileting schedule. In terms of home safety, it's important to advise the family or caretaker to remove clutter from the home as well as remove scatter rugs, which are trip hazards. And for some reason, nursing school exams are obsessed with scatter rugs. So definitely remember, no scattered rugs. Door locks should be installed out of sight and out of patient reach due to wandering behavior. There should be good lighting in the home, particularly over the stairs, and then step edges can be marked with colored tape to make it clear where those step edges are, which can help prevent falls.

Let's now review the key differences between dementia and delirium. Dementia is chronic, irreversible confusion that is caused by a neurodegenerative disease such as Alzheimer's disease, whereas delirium is temporary and reversible confusion that is caused by an underlying disorder such as an electrolyte imbalance or infection. So delirium is reversible when that underlying disorder is addressed. Dementia has a gradual onset as opposed to delirium, which has a sudden onset. With dementia, the individual's level of consciousness is unchanged, whereas, with delirium, alterations in level of consciousness are typically present. With delirium, the patient's behavior can be very disturbed. They can be easily distracted and may experience hallucinations, as opposed to dementia, where behavior is typically normal until the advanced stages of this disease.

All right. It's quiz time, and I've got five questions for you because we went over a lot of important information. Question number one, blank is the creation of false memories to fill in memory gaps. The answer is confabulation. Question number two, to prevent falls in the home, scatter rugs should be removed. True or false? The answer is true. Question number three, donepezil is a medication used to cure Alzheimer's disease. True or false? The answer is false. So donepezil can help improve cognition in a patient with Alzheimer's disease, but it will not cure the disease. Question number four, an altered level of consciousness is expected with dementia. True or false? The answer is false. So an altered level of consciousness often occurs with delirium but not with dementia. Question number five, delirium has a sudden onset and is reversible. True or false? The answer is true.

Okay. I hope you did great with that quiz. Thank you so much for watching and take care.

[BLOOPERS]Of the patients and [inaudible] that is caused by a [inaudible]. I don't know why neurodegenerative is so hard to say. A neurodegenerative-- oh, why can't I say the word?

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